Oteseconazole is under clinical development by Mycovia Pharmaceuticals and currently in the Phase II in clinical pathway. The characteristics of the clinical trial as well as other attributes related to the drug, regulations, and company play a fundamental role in ensuring the likelihood of transition that the drug moves from its current development stage to next.

According to GlobalData, the latest event to affect Oteseconazole’s likelihood of approval (LoA) and phase transition for Onychomycosis (Tinea Unguium) took place on 29 Apr 2022, which increased the likelihood that the drug progresses to the next phase in its clinical pathway and increased the likelihood of final approval for this indication.

GlobalData uses proprietary data and analytics to provide a complete picture of this assessment in their Oteseconazole Likelihood of Approval (LoA) and Phase Transition Success Rate (PTSR) Report.

Oteseconazole overview

Oteseconazole (Vivjoa) is a  potent and selective anti fungal agent. it is formulated as capsules for oral route of administration, Vivjoa is reduce the incidence of recurrent vulvovaginal candidiasis (RVVC) in females with a history of RVVC who are not of reproductive potential.    Oteseconazole (VT-1161) is under development for the treatment of fungal diseases such as Coccidioidomycosis, recurrent vulvovaginal candidiasis, Rhizopus oryzae infection causes zygomycosis, onychomycosis and chronic mucocutaneous candidiasis. It is a small molecule. The drug candidate is administered through oral route as a tablet. It acts by targeting lanosterol 14-alpha-demethylase or CYP51. The drug candidate is based on Metallophile technology platform. It was also under development for the treatment of athlete's foot (tinea pedis) and Coccidioidomycosis.

Mycovia Pharmaceuticals overview

Mycovia Pharmaceuticals(Mycoyia Pharmaceuticals) formerly known as Viamet Pharmaceuticals, is a subsidiary of Viamet Pharmaceuticals Holdings LLC, discovers and develops novel medicinal drugs based on metalloenzyme chemistry and biology technology platform. Its product portfolio includes clinical-stage compounds such as VT-1161, an oral inhibitor used for the treatment of onychomycosis and recurrent vulvovaginal candidiasis; VT-1129, an oral agent for the treatment of cryptococcal meningitis; VT-1598, an oral inhibitor to treat invasive fungal infections, including coccidioidomycosis. The company’s proprietary MIDAS technology (Metalloenzyme Inhibitor Design and Synthesis) enables to discover metalloenzyme inhibitors that target fungal CYP51 of both chronic and life threatening fungal infections. Mycoyia Pharmaceuticals is headquartered in Durham, North Carolina, the US.

Quick View Oteseconazole LOA Data

Report Segments
  • Innovator (NME)
Drug Name
  • Oteseconazole
Administration Pathway
  • Oral
Therapeutic Areas
  • Infectious Disease
Key Developers
Highest Development Stage
  • Marketed

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.