The Proteinase Activated Receptor 2 pipeline drugs market research report outlays comprehensive information on the Proteinase Activated Receptor 2 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Proteinase Activated Receptor 2 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Respiratory, Central Nervous System, Gastrointestinal, and Immunology which include the indications Asthma, Unspecified Respiratory Disorders, Migraine, Unspecified Neurologic Disorders, Inflammatory Bowel Disease, Metabolic Dysfunction-Associated Steatohepatitis (MASH), Psoriasis, and Unspecified Immunological Disorders. It also reviews key players involved in Proteinase Activated Receptor 2 targeted therapeutics development with respective active and dormant or discontinued products.
The Proteinase Activated Receptor 2 pipeline targets constitutes close to 15 molecules. Out of which, approximately 12 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase I, Preclinical, and Discovery stages are 4, 4, and 4 respectively. Similarly, the universities portfolio in Preclinical comprises 3 molecule.
Proteinase Activated Receptor 2 overview
Protease activated receptor 2 (PAR2) also known as coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a protein encoded by the F2RL1 gene. PARs (protease-activated receptors) are G-protein-coupled receptors for proteases from the circulation, inflammatory cells and epithelial tissues. PAR2 plays an important role in inflammation and pain. Pancreatic (trypsin I and II) and extrapancreatic (trypsin IV) trypsins, mast cell tryptase and coagulation factors VIIa and Xa cleave and activate PAR 2.
For a complete picture of Proteinase Activated Receptor 2’s drug pipeline, buy the report here.
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