Ricolinostat is under clinical development by Bristol-Myers Squibb and currently in Phase I for Chronic Lymphocytic Leukemia (CLL). According to GlobalData, Phase I drugs for Chronic Lymphocytic Leukemia (CLL) have a 69% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how Ricolinostat’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Ricolinostat (ACY-1215) is under development for the treatment of chemotherapy induced peripheral neuropathy, diabetic peripheral neuropathy, diabetic neuropathic pain, relapsed/refractory multiple myeloma, relapsed or refractory non-Hodgkin's lymphoma or Hodgkin's lymphoma, ovarian cancer, fallopian tube cancer, polycystic kidney disease, peritoneal cancer, metastatic breast cancer, Charcot-Marie-Tooth disease type II, pancreatic cancer and relapsed and refractory chronic lymphocytic leukemia (CLL). The drug candidate is administered orally as form of a liquid. It targets histone deacetylase 6 (HDAC6). The drug candidate is developed by using iterative biasing chemistry technology. The drug candidate was in development for the treatment of lung cancer, ovarian cancer, fallopian tube cancer, peritoneal cancer, cholangiocarcinoma and metastatic breast cancer.
Bristol-Myers Squibb overview
Bristol-Myers Squibb (BMS) is a specialty biopharmaceutical company that is engaged in discovery, development, licensing and manufacturing, marketing, distribution and sale of medicines and related medical products to patients with serious diseases. Its primary focus is on cancer, cardiovascular, immunology and fibrotic therapeutic projects. The company offers its products across the world to wholesalers, retail pharmacies, medical professionals, hospitals and government entities. BMS provides its products in the US, Europe, and Japan. The company conducts research to focus on the discovery and development of novel medicines that address serious diseases in areas of significant unmet medical need. BMS is headquartered in New York City, New York, the US.
For a complete picture of Ricolinostat’s drug-specific PTSR and LoA scores, buy the report here.