RLY-4008 is a small molecule commercialized by Relay Therapeutics, with a leading Phase II program in Bile Duct Cancer (Cholangiocarcinoma). According to Globaldata, it is involved in 1 clinical trial, which is ongoing. GlobalData uses proprietary data and analytics to provide a complete picture of RLY-4008’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
The revenue for RLY-4008 is expected to reach an annual total of $29 mn by 2034 globally based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
RLY-4008 is under development for the treatment of metastatic solid tumors like intrahepatic cholangiocarcinoma and breast cancer. It is administered by oral route. The drug candidate acts by targeting fibroblast growth factor receptor 2 (FGFR2). It is being developed based on Dynamo platform.
It was under development for the treatment of gastric cancer, endometrial cancer.
Relay Therapeutics Overview
Relay Therapeutics is a biotechnology company that develops therapies for multiple diseases. The company’s technology enables the rational allosteric drug discovery process to design better drugs. It leverages insights from protein motion to develop its products. Relay Therapeutics brings together scientific advances including biophysics, chemistry, structural biology, computation, and biology to enable new approaches for therapeutic intervention in disease. Its research focuses on the discovery and development of oncology therapeutics. The company partners with various healthcare companies. Relay Therapeutics is headquartered in Cambridge, Massachusetts, the US.
The company reported revenues of (US Dollars) US$3 million for the fiscal year ended December 2021 (FY2021), a decrease of 96.3% over FY2020. The operating loss of the company was US$364.7 million in FY2021, compared to an operating loss of US$55.8 million in FY2020. The net loss of the company was US$363.9 million in FY2021, compared to a net loss of US$52.4 million in FY2020. The company reported revenues of US$0.3 million for the third quarter ended September 2022, a decrease of 5.8% over the previous quarter.
For a complete picture of RLY-4008’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.