S-055746 is under clinical development by Novartis and currently in Phase I for Relapsed Chronic Lymphocytic Leukemia (CLL). According to GlobalData, Phase I drugs for Relapsed Chronic Lymphocytic Leukemia (CLL) have a 73% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how S-055746’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
S-055746 overview
S-055746 is under development for the treatment of refractory and relapsed chronic lymphocytic leukaemia, B-cell Non-Hodgkin lymphoma such as mantle cell lymphoma, follicular lymphoma, small lymphocytic lymphoma or marginal zone lymphoma, diffuse large B-cell lymphoma, relapsed or refractory myeloma for those who have failed prior hypomethylating therapy. The drug candidate is administered orally. It acts by targeting B-cell leukemia/lymphoma-2 (Bcl-2). It was under development for the treatment of relapsed or refractory acute myeloid leukaemia, diffuse large B-cell lymphoma and myelodysplastic syndrome.
Novartis overview
Novartis is a healthcare company that focuses on the discovery, development, manufacture and marketing of prescription and generic pharmaceutical products and eye care products. It provides drugs for the treatment of cancer, cardiovascular diseases, dermatological conditions, neurological disorders, ophthalmic and respiratory diseases, hematologic diseases, solid tumors, immune disorders, and infections, among others. The company offers generic medicines and biosimilars through Sandoz. Novartis conducts research in various disease areas through The Novartis Institutes for BioMedical Research (NIBR). The company operates through a network of subsidiaries and offices across the Americas, Europe, the Middle East, Africa, and Asia-Pacific. Novartis is headquartered in Basel, Switzerland.
For a complete picture of S-055746’s drug-specific PTSR and LoA scores, buy the report here.
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