SFX-01 is under clinical development by Stalicla and currently in Phase I for Autism Spectrum Disorder (ASD). According to GlobalData, Phase I drugs for Autism Spectrum Disorder (ASD) have a 91% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how SFX-01’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

SFX-01 overview

SFX-01 is under development for the treatment of human epidermal growth factor receptor 2 (her2) negative metastatic breast cancer, chronic kidney disease, glioblastoma, juvenile myelomonocytic leukaemia (JMML), rhabdomyosarcoma, autism spectrum disorder (ASD) Phenotype 2, colorectal cancer. It is administered orally. The drug candidate is a stabilized synthetic version of sulforaphane. The drug candidate acts by targeting the mutated kelch like ECH associated protein 1 (KEAP1). The drug candidate is developed based on DEPI (Databased Endophenotyping Patient Identification) technology and Sulforadex technology.

It was also under development for the treatment of Parkinson's disease, chronic obstructive pulmonary disease (COPD), acute lymphoblastic leukemia (ALL), multiple sclerosis, osteoarthritis, osteoporosis, cerebral vasospasm, the incidence of delayed cerebral ischemia, prostate cancer, and non-alcoholic fatty liver disease (NAFLD), acute myelocytic leukemia, subarachnoid hemorrhage,community acquired pneumonia and acute respiratory distress syndrome associated with COVID-19 and cardiovascular diseases.

Stalicla overview

Stalicla is a biotechnology company developing precision medicine treatments for patients with Neurodevelopmental disorders. Stalicla is headquartered in Geneva, Switzerland.

For a complete picture of SFX-01’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 2 September 2023

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.