Sodium zirconium cyclosilicate is under clinical development by AstraZeneca and currently in the Phase III in clinical pathway. The characteristics of the clinical trial as well as other attributes related to the drug, regulations, and company play a fundamental role in ensuring the likelihood of transition that the drug moves from its current development stage to next.
According to GlobalData, the latest event to affect Sodium zirconium cyclosilicate’s likelihood of approval (LoA) and phase transition for Chronic Kidney Disease (Chronic Renal Failure) took place on 12 Dec 2022, which decreased the likelihood that the drug progresses to the next phase in its clinical pathway and decreased the likelihood of final approval for this indication.
GlobalData uses proprietary data and analytics to provide a complete picture of this assessment in their Sodium zirconium cyclosilicate Likelihood of Approval (LoA) and Phase Transition Success Rate (PTSR) Report.
Sodium zirconium cyclosilicate overview
Sodium zirconium cyclosilicate (Lokelma) is a selective oral sorbent. It is formulated as powder for suspension for oral route of administration. Lokelma is indicated for the treatment of hyperkalaemia in adults and chronic kidney disease.
Sodium zirconium cyclosilicate (Lokelma) was under development for the treatment of chronic kidney disease, hyperkalemia in Australia, South Korea, and Taiwan. The drug candidate is a non-systemic sorbent which is developed based on ZrSi technology platform.
AstraZeneca is a biopharmaceutical company, which is focused on discovery, production and commercialization of a range of prescription drugs. It develops products related to therapy areas such as respiratory, cardiovascular, renal and metabolic diseases, cancer, autoimmune, infection and neurological diseases. The company’s product portfolio includes biologics, prescription pharmaceuticals and vaccines. AstraZeneca sells its products through wholly-owned local marketing companies, distributors and local representative offices. The company markets its products to primary care and specialty care physicians. The COVID-19 Vaccine AstraZeneca has been approved for conditional marketing or emergency use. The company operates in Europe, the Americas, Asia, Africa and Australasia. AstraZeneca is headquartered in Cambridge, Cambridgeshire, the UK.
Quick View Sodium zirconium cyclosilicate LOA Data
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