Spesolimab is under clinical development by Boehringer Ingelheim International and currently in Phase III for Hidradenitis Suppurativa. According to GlobalData, Phase III drugs for Hidradenitis Suppurativa have a 100% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. GlobalData’s report assesses how Spesolimab’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Spesolimab overview

Spesolimab (Spevigo) is an interleukin-36 receptor antagonist. It is formulated as injection solution and concentration for solution for the intravenous route of administration. Spevigo is indicated for the treatment of generalized pustular psoriasis flares in adults.

Spesolimab (BI-655130) is under development for the treatment of moderate or severe hidradenitis suppurativa, atopic dermatitis, generalized pustular psoriasis (GPP) flares, plaque psoriasis, Crohn's disease, Netherton Syndrome and unspecified indication. It is administered through intravenous and subcutaneous routes as a solution. The drug candidate acts by targeting interleukin-36 receptor.

It was under development for atopic dermatitis through subcutaneous route, ulcerative colitis and palmoplantar pustulosis.

Boehringer Ingelheim International overview

Boehringer Ingelheim International (Boehringer), a subsidiary of CH Boehringer Sohn AG & Co KG, is a pharmaceutical company that develops, manufactures and markets of pharmaceuticals, parasiticides, vaccines and therapeutics for unmet medical needs. It offers a wide range of products including human diseases, animal health care products and biopharmaceuticals. The company’s products are used for the treatment central nervous system disorders, cardiometabolic diseases, respiratory diseases, cancer, immunology, and retinal diseases among others. It also offers animal healthcare products for Swine, Ruminant, Poultry, Horses, Pets etc. It operates facilities for manufacture pharmaceuticals and medical products. Boehringer is headquartered in Ingelheim am Rhein, Rheinland-Pfalz, Germany.

For a complete picture of Spesolimab’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 2 September 2023

Premium Insights


The gold standard of business intelligence.

Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.


GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.