Sunvozertinib is under clinical development by Dizal Pharmaceutical and currently in Phase II for Non-Small Cell Lung Cancer. According to GlobalData, Phase II drugs for Non-Small Cell Lung Cancer have a 38% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Sunvozertinib’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Sunvozertinib overview

Sunvozertinib (Zegfrovy) acts as an anti-neoplastic agent. It is formulated as tablets for the oral route of administration. Zegfrovy is indicated for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion (Exon20ins) mutations, whose disease has progressed on or after platinum-based chemotherapy.

Sunvozertinib (DZD-9008) is under development for the treatment of advanced non-small cell lung cancer. The drug candidate acts by targeting epidermal growth factor receptor (EGFR) with Exon 20 insertions. It is administered orally in form of tablet. It was under development for non-Hodgkin B-cell lymphomas including relapsed and refractory chronic lymphocytic leukemia, mantle cell lymphoma, marginal zone B-cell lymphoma and small lymphocytic lymphoma.

Dizal Pharmaceutical overview

Dizal Pharmaceutical (Dizal) is a biopharmaceutical company. It focuses on research, development, and commercialization of therapies to treat cancer and immunological diseases. The company’s lead product candidate ZEGFROVY, which is at marketing approval stage for treatment of solid tumors. Its product pipeline includes other drug programs such as JAUKPO to treat hematological malignancy, solid tumors, and immunological diseases; DZD8586 for treatment of hematological malignancy; and DZD2269 and DZD1516 to treat solid tumors. The company operates with additional facilities in Beijing, Wuxi, Chengdu, China. Dizal is headquartered in Shanghai, China.

For a complete picture of Sunvozertinib’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.