TAS-117 is under clinical development by Taiho Pharmaceutical and currently in Phase II for Breast Cancer. According to GlobalData, Phase II drugs for Breast Cancer have a 34% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how TAS-117’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
TAS-117 is under development for the treatment of solid tumors including FGFR1 squamous cell lung cancer, ovarian clear cell carcinoma, endometrial cancer, breast cancer, colon cancer, ovarian cancer, cervical cancer, head and neck cancer, thyroid cancer, chondrosarcoma and g-PTEN aberrations cancer. It is a small molecule administered by orally. The drug candidate acts as selective non-ATP competitive inhibitor of AKT. It was under development for the treatment of gastric cancer and multiple myeloma.
Taiho Pharmaceutical overview
Taiho Pharmaceutical (Taiho), a subsidiary of Otsuka Group, develops and markets pharmaceutical products in the field of cancer, allergy, immunology and urology. Its product portfolio includes pharmaceutical products such as anti-allergic agents, anti-tumor agents, H2 receptor antagonists, antibiotics and medical devices; and consumer health products such as herbal digestive medicine, topical analgesics, antifungal cream and herbal medicine powder, among others. Taiho has production facilities in Tokushima, Saitama, Okayama, Kitajima and Inuyama. It operates through its subsidiaries situated worldwide including Japan, China, Canada, Singapore, the UK and the US. Taiho is headquartered in Tokyo, Japan.
For a complete picture of TAS-117’s drug-specific PTSR and LoA scores, buy the report here.