Vilobelimab is under clinical development by InflaRx and currently in the Phase I and Phase II in clinical pathway. The characteristics of the clinical trial as well as other attributes related to the drug, regulations, and company play a fundamental role in ensuring the likelihood of transition that the drug moves from its current development stage to next.

According to GlobalData, the latest event to affect Vilobelimab’s likelihood of approval (LoA) and phase transition for Pyoderma Gangrenosum took place on 08 Jul 2022, which increased the likelihood that the drug progresses to the next phase in its clinical pathway and increased the likelihood of final approval for this indication.

GlobalData uses proprietary data and analytics to provide a complete picture of this assessment in their Vilobelimab Likelihood of Approval (LoA) and Phase Transition Success Rate (PTSR) Report.

Vilobelimab overview

Vilobelimab (IFX-1) is under development for the treatment of advanced or metastatic cutaneous squamous cell carcinoma (cSCC), granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), anti-neutrophil cytoplasmic antibody-associated vasculitis, septic organ dysfunction, hidradenitis suppurativa, systemic inflammatory response syndrome (SIRS) induced organ dysfunction (sepsis, septic shock, inflammation, multiple organ dysfunction), acute lung injury, pyoderma gangraenosum, chronic inflammation, cancer and coronavirus disease 2019 (COVID-19). It is administered through intravenous route. The drug candidate is a humanized monoclonal antibody. It was under development for community-acquired pneumonia.

It was under development for anti-neutrophil cytoplasmic antibody-associated vasculitis and hidradenitis suppurativa.

InflaRx overview

InflaRx is a clinical-stage bio pharmaceutical company that develops therapies in the field of acute and chronic inflammation. The company offers the development of monoclonal antibodies targeting activation products of the complement system for application in threatening inflammatory diseases and certain orhan drug indications. Its pipeline products includes IFX-1 and IFX-2. InflaRx operates in various research and development programs in life science sectors. The company offers antibodies that are able to fulfil requirements determined by InflaRx for generation of suitable drug candidates. It offers research services through collaboration with universities and biotech companies. InflaRx is headquartered in Jena, Germany.

Quick View Vilobelimab LOA Data

Report Segments
  • Innovator
Drug Name
  • Vilobelimab
Administration Pathway
  • Intravenous
Therapeutic Areas
  • Cardiovascular
  • Dermatology
  • Immunology
  • Infectious Disease
  • Oncology
  • Other Diseases
  • Respiratory
Key Developers
  • Sponsor Company: InflaRx
  • Originator: InflaRx and Beijing Mabworks Biotech
Highest Development Stage
  • Phase III

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.