Vofatamab is under clinical development by Fusion Pharmaceuticals and currently in Phase I for Refractory Multiple Myeloma. According to GlobalData, Phase I drugs for Refractory Multiple Myeloma have a 78% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how Vofatamab’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Vofatamab overview
Vofatamab (B-701, RG-7444) is under development for the treatment of non muscle invasive bladder cancer and relapsed/refractory multiple myeloma. It is a human IgG1 monoclonal antibody. The therapeutic candidate is administered through the intravenous route as an infusion. It acts by targeting FGFR3. It was also under development for the treatment of achondroplasia and locally advanced or metastatic solid malignancies. It was also under development for the treatment of metastatic urothelial cell carcinoma of the urothelium, including the urinary bladder, urethra, ureter, and/or renal pelvis.
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Fusion Pharmaceuticals overview
Fusion Pharmaceuticals is a clinical-stage biopharmaceutical company which develops targeted alpha-particle radio therapeutics for the treatment of cancers. It offers pipeline products such as FPI-1434, FPI-2059 and FPI-1966. The company’s pipeline products treat multiple cancers like head and neck bladder cancer, colorectal cancer and gastric cancers. It aslo include mono therapy and combination therapy. Fusion Pharmaceuticals carters its products under brand Keytruda. It has its operations in the US and Canada. Fusion Pharmaceuticals is headquartered in Hamilton, Ontario, Canada.
For a complete picture of Vofatamab’s drug-specific PTSR and LoA scores, buy the report here.
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