VP-01 is under clinical development by Vicore Pharma and currently in the Phase I in clinical pathway. The characteristics of the clinical trial as well as other attributes related to the drug, regulations, and company play a fundamental role in ensuring the likelihood of transition that the drug moves from its current development stage to next.

According to GlobalData, the latest event to affect VP-01’s likelihood of approval (LoA) and phase transition for Pulmonary Arterial Hypertension took place on 19 Sep 2022, which decreased the likelihood that the drug progresses to the next phase in its clinical pathway and decreased the likelihood of final approval for this indication.

GlobalData uses proprietary data and analytics to provide a complete picture of this assessment in their VP-01 Likelihood of Approval (LoA) and Phase Transition Success Rate (PTSR) Report.

VP-01 overview

VP-01 is under development for the treatment of idiopathic pulmonary fibrosis and pulmonary arterial hypertension (PAH). It is administered through oral and intravenous route. The drug candidate is a small non-peptide. It is highly selective for the angiotensin II receptor type-2 (AT2) receptor. The drug is based on a receptor targeting technology which includes molecules with agonistic action to the AT2 receptor. It was under development for the treatment of coronavirus disease 2019 (COVID-19).

Vicore Pharma overview

Vicore Pharma formerly Pharmacore, a subsidiary of Vicore Pharma Holding AB, operates as a biotechnology company focused on the development of orphan drugs for the treatment of fibrotic diseases. Its lead product candidate C21 that stimulates the AT2 receptors is used for the treatment of idiopathic pulmonary fibrosis (IPF). Its portfolio includes small molecules with potential indications which are used in various therapeutic indications such as anti-inflammation, neuro protection, neuro regeneration, and cardiovascular diseases. The company seeks to work in collaboration with pharmaceutical companies to accelerate the development and licensing opportunities for its pipeline products. Vicore Pharma is headquartered in Molndal, Sweden.

Quick View VP-01 LOA Data

Report Segments
  • Innovator
Drug Name
  • VP-01
Administration Pathway
  • Intravenous
  • Oral
Therapeutic Areas
  • Cardiovascular
  • Infectious Disease
  • Respiratory
Key Developers
Highest Development Stage
  • Phase II

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.