VXM-01 is under clinical development by Vaximm and currently in Phase II for Recurrent Glioblastoma Multiforme (GBM). According to GlobalData, Phase II drugs for Recurrent Glioblastoma Multiforme (GBM) have a 24% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how VXM-01’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

VXM-01 overview

VXM-01 is under development for the treatment of recurrent glioblastoma multiforme, and metastatic colorectal cancer. The vaccine candidate is administered through oral route. It is a DNA Vaccine comprising the attenuated Salmonella typhi strain Ty21a transformed by a plasmid that contains a DNA encoding the vascular endothelium growth factor receptor 2 (VEGF2). It is developed based on oral T-cell vaccine technology platform. It was also under development for the treatment of pancreatic cancer.

For a complete picture of VXM-01’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.