Taste Masking Acetaminophen Chewable Tablets Using Maltitol Plus Intense Sweetener Synergy

Use of technologies to mask the bitterness of active pharmaceutical ingredients (API) is limited in pediatric formulations by a lack of safety data covering children, in comparison to adults.

Acetaminophen (APAP) is a common medication used to treat infants for pain and fever. Its bitterness often leads to complex formulations to encourage adherence. Making tastes with a combination of common sweetener sucralose and bulk sweetener maltitol is beneficial because both of these ingredients are already present in paediatric medicines.

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