22 October 2020
Anvisa, the Brazilian healthcare regulator, has reported the death of a volunteer involved in AstraZeneca and University of Oxford Covid-19 vaccine trial being carried out in Brazil. Anvisa has confirmed that trial will continue as the volunteer was part of the placebo group. This was later confirmed by the University of Oxford, according to Reuters.
Poseida Therapeutics and TScan Therapeutics are collaborating to explore the efficacy of TCR-T cell therapies to treat Covid-19. The partnership will leverage TScan’s TCR sequences and immunodominant epitopes and Poseida’s allogeneic T cell approach to advance TCR-T cell therapies against Covid-19.
Dr Juan Carlos Zevallos, the health minister of Ecuador, announced that the country has entered into Covid-19 vaccine supply agreements with pharmaceutical companies, such as Pfizer and BioNTech, for Covid-19 vaccines. The country is also collaborating with Chinese laboratories for supplies and is funded by the Inter-American Development Bank to gain access to the COVAX vaccine, he added.
Researchers from the University of Tennessee Health Science Center and the University of New Mexico have identified zuclopenthixol, nebivolol, and amodiaquine drugs as efficacious therapeutics to fight the SARS-CoV-2 virus. The drugs are already approved for human use and have been found to be effective in the earlier stages of Covid-19.