Sanofi Pasteur and US Naval Centre to Develop Diarrhoea Vaccine

13 April 2010 (Last Updated April 13th, 2010 18:30)

Sanofi Pasteur has entered into a four-year strategic partnership with the US Naval Medical Research Center (NMRC) to develop a diarrhoea vaccine. The core enterotoxigenic Escherichia coli (ETEC) adhesin vaccine technology, developed by the NMRC, had been licensed to Sanofi along with a

Sanofi Pasteur has entered into a four-year strategic partnership with the US Naval Medical Research Center (NMRC) to develop a diarrhoea vaccine.

The core enterotoxigenic Escherichia coli (ETEC) adhesin vaccine technology, developed by the NMRC, had been licensed to Sanofi along with another technology that packages the adhesin with a toxoid vaccine component co-developed by NMRC and the University of Colorado Denver.

Sanofi Pasteur president and CEO Wayne Pisano said that the company will expedite the development of this vaccine for eventual licensure and sales worldwide.

"This multi-year project will provide a solid basis for launching clinical development," Pisano said

"We believe that this vaccine has the potential to curtail the number and severity of food-borne illnesses due to ETEC, and it may also decrease the risk of post-infectious irritable bowel syndrome, which afflicts one in ten who experience travellers' diarrhoea."

Following the successful four-year pre-clinical research, full-scale clinical development of a multivalent adhesin-based ETEC vaccine will be initiated.