A joint initiative to develop a computer-simulated skin model that will help eliminate the need for the pharmaceutical industry to use animals in contact allergy testing has been formed between France-based Bio-Modeling Systems and software developer Persistent Systems.
The move comes less than two weeks after the European Union banned the import and sale of cosmetics containing ingredients tested on animals.
Bio-Modeling Systems will combine the outputs of its computer-assisted deductive integration (CADI) system, a technology that delivers new disease concepts and corresponding treatments, with Persistent’s new software platform, Cell-in-Silico, to develop the skin cell interplay mechanisms.
The venture is the first collaborative effort that combines non-mathematical heuristic modelling with mathematical modelling, designed to increase the success rates of drug discovery.
Persistent Systems CEO and managing director Dr Anand Deshpande said; "Bio-Modeling Systems and Persistent Systems have come together to develop a much needed solution that will address the pharma and cosmetic industries’ need for predictive modeling of skin in silico."
"Bio-Modeling Systems scientists have pioneered heuristic biological modeling with their CADI platform. By coupling this with Persistent Systems’ strength in mathematical modeling and IT, we will develop a viable in silico alternative to animal testing."
Bio-Modeling Systems CSO Dr Francois Iris added; "For the first time ever, mechanistic modeling and dynamics engineering will be merged, bringing a whole new level of understanding to the multi-scale biological space, enabling us to develop a fully integrated, outstanding set of solutions to previously intractable biotechnological problems."
Image: The European Union has banned the import and sale of cosmetics containing ingredients tested on animals.