SION-109 is under clinical development by Sionna Therapeutics and currently in Phase I for Cystic Fibrosis. According to GlobalData, Phase I drugs for Cystic Fibrosis have a 74% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how SION-109’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
SION-109 overview
SION-109 is under development for the treatment of cystic fibrosis. The drug candidate is a small molecule which acts by targeting intracellular loop 4 (ICL4) of the cystic fibrosis transmembrane conductance regulator (CFTR).
Sionna Therapeutics overview
Sionna Therapeutics (Sionna) is a developer of novel small molecule therapies to treat cystic fibrosis (CF). Sionna is headquartered in Natick, Massachusetts, the US.
For a complete picture of SION-109’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
