The Acetyl Coenzyme A Synthetase Cytoplasm pipeline drugs market research report outlays comprehensive information on the Acetyl Coenzyme A Synthetase Cytoplasm targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Acetyl Coenzyme A Synthetase Cytoplasm pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Central Nervous System, and Infectious Disease which include the indications Solid Tumor, Triple-Negative Breast Cancer (TNBC), Substance (Drug) Abuse, Post-Traumatic Stress Disorder (PTSD), and Malaria. It also reviews key players involved in Acetyl Coenzyme A Synthetase Cytoplasm targeted therapeutics development with respective active and dormant or discontinued products.
The Acetyl Coenzyme A Synthetase Cytoplasm pipeline targets constitutes close to six molecules. Out of which, approximately five molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase I, Preclinical, and Discovery stages are 1, 3, and 1 respectively. Similarly, the universities portfolio in Preclinical comprises 1 molecule.
Acetyl Coenzyme A Synthetase Cytoplasm overview
Acetyl-Coenzyme A Synthetase, Cytoplasmic (ACSS2) is an enzyme that plays a crucial role in cellular metabolism, specifically in the synthesis of acetyl-Coenzyme A (acetyl-CoA). Acetyl-CoA is a central metabolite involved in various biochemical pathways, including the tricarboxylic acid (TCA) cycle, fatty acid synthesis, and histone acetylation. ACSS2 is primarily localized in the cytoplasm of cells, where it catalyzes the conversion of acetate to acetyl-CoA. This enzymatic activity allows cells to utilize acetate, a short-chain fatty acid, as a substrate for energy production and various biosynthetic processes. Beyond its role in energy metabolism, ACSS2 has been implicated in the regulation of cellular processes such as gene expression and lipid metabolism. The enzyme has been found to contribute to histone acetylation, impacting chromatin structure and gene transcription. In cancer cells and other rapidly proliferating cells, ACSS2 has been shown to play a role in supporting the increased demand for acetyl-CoA necessary for accelerated growth.
For a complete picture of Acetyl Coenzyme A Synthetase Cytoplasm’s drug pipeline, buy the report here.
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