Aldesleukin is under clinical development by Iltoo Pharma and currently in Phase III for Amyotrophic Lateral Sclerosis. According to GlobalData, Phase III drugs for Amyotrophic Lateral Sclerosis have a 33% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. GlobalData’s report assesses how Aldesleukin’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
ILT-101 is under development for the treatment of autoimmune and inflammatory diseases including type I diabetes, acute respiratory distress syndrome due to Coronavirus disease 2019 (COVID-19), relapsing remitting multiple sclerosis, recurrent miscarriage, systemic lupus erythematosus, allergic rhino-conjunctivitis, rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus, psoriasis, Behcet disease, Wegener granulomatosis, Crohn's disease, ulcerative colitis, autoimmune hepatitis, sclerosing cholangitis, Gougerot-sjogren, systemic sclerosis, idiopathic thrombocytopenic purpur, bipolar disorder and amyotrophic lateral sclerosis. It is administered by subcutaneous route and formulated as powder for solution as an injection. The drug candidate is a human recombinant Interleukin-2 which acts by targeting interleukin receptor2. It was also under development for Takayasu disease.
For a complete picture of Aldesleukin’s drug-specific PTSR and LoA scores, buy the report here.