Allogeneic Donor-Derived T-Cells Transduced With Bivalent Lentiviral Vector (CD19/CD22-BBz) Chimeric Antigen Receptor (CAR) is under clinical development by Orca Biosystems and currently in Phase I for B-Cell Acute Lymphocytic Leukemia (B-Cell Acute Lymphoblastic Leukaemia). According to GlobalData, Phase I drugs for B-Cell Acute Lymphocytic Leukemia (B-Cell Acute Lymphoblastic Leukaemia) have a 90% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how Allogeneic Donor-Derived T-Cells Transduced With Bivalent Lentiviral Vector (CD19/CD22-BBz) Chimeric Antigen Receptor (CAR)’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Allogeneic Donor-Derived T-Cells Transduced With Bivalent Lentiviral Vector (CD19/CD22-BBz) Chimeric Antigen Receptor (CAR) overview
Gene-modified cell therapy is under development for the treatment of B-cell acute lymphoblastic leukemia (ALL). It is administered through intravenous route and it comprises of allogenic donor derived CD19/CD22-chimeric antigen receptors (CAR) T cells transduced with bivalent lentiviral vector.
Orca Biosystems overview
Orca Biosystems (Orca Bio) is a clinical-stage biotechnology company developing a pipeline of high precision allogeneic cell therapy products that are designed to safely replace patients’ diseased blood and immune system with a healthy one. The company is headquartered in Menlo Park, California, the US.
For a complete picture of Allogeneic Donor-Derived T-Cells Transduced With Bivalent Lentiviral Vector (CD19/CD22-BBz) Chimeric Antigen Receptor (CAR)’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
