Azeliragon is under clinical development by Cantex Pharmaceuticals and currently in Phase II for Refractory Brain Metastasis. According to GlobalData, Phase II drugs for Refractory Brain Metastasis does not have sufficient historical data to build an indication benchmark PTSR for Phase II. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the Azeliragon LoA Report. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Azeliragon is under development for the treatment of hospitalized patients with severe COVID-19, cancer-treatment related cognitive decline, chronic obstructive pulmonary disease (COPD) and steroid refractory asthma, metastatic pancreatic cancer, glioblastoma multiforme, gliosarcoma, triple negative breast cancer, brain metastasis and breast cancers. The drug candidate is administered through oral route and acts by targeting RAGE (receptor for advanced glycation endproducts). The drug is developed based on the TTP translational technology. It was under development for the treatment of Alzheimer’s disease (dementia with diabetes) and diabetic nephropathy.
Cantex Pharmaceuticals overview
Cantex Pharmaceuticals, formerly ParinGenix is a clinical stage biopharmaceutical company. The company discovers and develops proprietary pharmaceuticals for the treatment of cancers and other disorders. Its pipeline products include CX-01 a proprietary combination of disulfiram and copper that is in Phase II clinical trial for the treatment of recurrent glioblastoma; and completed Phase 1 trial in metastatic prostate cancer and breast cancer. Cantex Pharmaceuticals also develops CX-01 a polysaccharide used for the treatment of acute myeloid leukemia (AML), traumatic brain injury and other blood disorders. The company offers its products across the US. Cantex Pharmaceuticals is headquartered in Weston, Florida, the US
For a complete picture of Azeliragon’s drug-specific PTSR and LoA scores, buy the report here.