BioRestorative Therapies has patented methods for developing and using stem cell lines to treat degenerative and metabolic disorders like obesity and diabetes. The patent also covers screening compounds that regulate various processes, including modifying metabolic activity of human brown fat adipocytes. GlobalData’s report on BioRestorative Therapies gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on BioRestorative Therapies, was a key innovation area identified from patents. BioRestorative Therapies's grant share as of February 2024 was 54%. Grant share is based on the ratio of number of grants to total number of patents.
Identifying compounds that modify metabolic activity of human brown fat
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A recently granted patent (Publication Number: US11851682B2) discloses a method for identifying compounds that modify the metabolic activity of human brown fat adipocytes. The method involves differentiating human stem cells from brown adipose tissue into brown fat adipocytes in a hypoxic environment and specific differentiation medium. The differentiated cells are then exposed to various compounds, and their metabolic activity is assessed to identify compounds that alter their function. The method focuses on measuring adipogenesis and gene expression of markers related to adipogenesis to evaluate the effects of the compounds on brown fat adipocytes.
Furthermore, the patent claims cover a wide range of compounds that can be tested using this method, including proteins, antibodies, peptides, nucleic acids, hormones, and small organic molecules. The compounds can be natural-based, synthetic, recombinant, or a combination thereof. By utilizing this method, researchers can potentially discover novel compounds that modulate the metabolic activity of human brown fat adipocytes, offering insights into potential therapeutic targets for conditions related to metabolism and energy expenditure. The patent also emphasizes the importance of utilizing a xenogenic animal product-free environment during the differentiation process, highlighting the significance of maintaining a controlled and specific experimental setting for accurate results.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
