Cusatuzumab is under clinical development by OncoVerity and currently in Phase II for Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia). According to GlobalData, Phase II drugs for Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia) have a 30% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Cusatuzumab’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Cusatuzumab overview

Cusatuzumab (ARGX-110) is under development for the treatment of acute myeloid leukemia(AML) and high risk myelodysplatic syndrome. The therapeutic candidate is administered through intravenous or subcutaneous route. It is a glyco-engineered fully human antibody developed based on SIMPLE antibody platform. ARGX-110 is equipped with Potelligent to enhance its ability to destroy CD70-positive tumor cells.

The drug candidate was also under development for chronic myelocytic leukemia (CML), inflammatory and autoimmune disorders, Inflammation,  Sezary syndrome (cutaneous T-cell lymphoma), epithelial tumor, chronic myelomonocytic leukemia (CMML), solid tumors such as renal cell carcinoma, acute promyelocytic leukemia, platinum-refractory ovarian cancer, head and neck cancer, nasopharyngeal carcinoma, myoepithelial carcinoma, mesothelioma, hematological malignancies including refractory Waldenstrom’s macroglobulinemia (WM), relapsed/refractory T-cell lymphomas such as angioimmunoblastic T-cell lymphoma (AITL).

OncoVerity overview

OncoVerity is a healthcare company that involved in providing research and development of anti-CD70 antibody. The company is headquartered in Aurora, Colorado, the US.

For a complete picture of Cusatuzumab’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 20 February 2024

Premium Insights


The gold standard of business intelligence.

Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.


GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.