Daiichi Sankyo has been granted a patent for intermediates and processes that enable the easy synthesis of compounds of Formula 2. The compounds have specific structural characteristics, including the presence of certain substituents and functional groups. GlobalData’s report on Daiichi Sankyo gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Daiichi Sankyo, Cancer treatment biomarkers was a key innovation area identified from patents. Daiichi Sankyo's grant share as of September 2023 was 43%. Grant share is based on the ratio of number of grants to total number of patents.
A recently granted patent (Publication Number: US11739088B2) discloses a compound of Formula 2 and methods for preparing compounds of Formula 2, Formula 3, Formula 4, and Formula 5. The patent claims cover various aspects of the preparation process, including the use of specific reagents, solvents, and coupling agents.
Claims 1 and 13 describe a compound of Formula 2 and a compound of Formula 2a, respectively. The patent provides methods for preparing these compounds, as described in Claims 2 and 3. Claim 3 specifies the use of trifluoroacetic anhydride as the acetic anhydride in the preparation process.
Similarly, Claims 4 and 14 describe a compound of Formula 3 and a compound of Formula 2e, respectively. The patent discloses a method for preparing these compounds, as stated in Claim 5. Claim 5 also mentions the use of trifluoroacetic anhydride as the acetic anhydride.
Furthermore, Claim 6 specifies that acetonitrile is a suitable solvent for the preparation of the compound of Formula 3. This claim provides valuable information regarding the choice of solvent in the synthesis process.
Claims 7 and 8 introduce methods for preparing compounds of Formula 4 and Formula 5, respectively. Claim 9 mentions the use of trifluoroacetic anhydride as the acetic anhydride in the preparation of the compound of Formula 5. Additionally, Claim 10 highlights acetonitrile as a suitable solvent for the synthesis of the compound of Formula 5.
Moreover, Claim 11 provides a list of suitable coupling agents for the preparation of the compound of Formula 5, including BOP, PyBOP, PyBrOP, TBTU, HBTU, HATU, COMU, or TFFH. Claim 12 specifies PyBOP as a preferred coupling agent for the synthesis process.
In summary, the granted patent (Publication Number: US11739088B2) discloses compounds of Formula 2, Formula 2a, Formula 2e, Formula 3, Formula 4, and Formula 5, along with methods for their preparation. The patent claims cover various aspects of the synthesis process, including the use of specific reagents, solvents, and coupling agents. This information can be valuable for researchers and professionals in the field who are interested in the development and production of these compounds.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
