Delpacibart etedesiran is under clinical development by Avidity Biosciences and currently in Phase II for Myotonic Dystrophy. According to GlobalData, Phase II drugs for Myotonic Dystrophy does not have sufficient historical data to build an indication benchmark PTSR for Phase II. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the Delpacibart etedesiran LoA Report. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Delpacibart etedesiran overview

Delpacibart etedesiran (AOC-1001) is under development for the treatment of myotonic dystrophy type 1. It is administered through intravenous route. The drug candidate is being developed based on antibody oligonucleotide conjugate (AOC) platform, containing mAb that targets cells expressing transferrin receptor 1 (TfR1) to deliver an siRNA targeting the mRNA encoding DMPK.

Avidity Biosciences overview

Avidity Biosciences is a biotech company that develops antibody oligonucleotide conjugates (AOCs). The company product pipeline include AOC 1001, AOC 1044 and AOC 1020. Its pipeline treats myotonic dystrophy type 1 (DM1), duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). Avidity Biosciences carries out AOC components such as monoclonal, linker, siRNA and PMO. The company has research collaborations with leading pharma companies, to discover antibody-based drug candidates against various therapeutic targets. Avidity Biosciences is headquartered in San Diego, California, the US.

For a complete picture of Delpacibart etedesiran’s drug-specific PTSR and LoA scores, buy the report here.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.