Efinopegdutide is a recombinant protein commercialized by Merck, with a leading Phase II program in Obesity. According to Globaldata, it is involved in 7 clinical trials, of which 5 were completed, 1 is ongoing, and 1 is planned. GlobalData uses proprietary data and analytics to provide a complete picture of Efinopegdutide’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
The revenue for Efinopegdutide is expected to reach an annual total of $12 mn by 2038 in the US based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
Efinopegdutide is under development for the treatment of nonalcoholic steatohepatitis, obesity, nonalcoholic fatty liver disease (NAFLD), and type 2 diabetes. The therapeutic candidate is administered subcutaneously. The drug candidate is a long acting glucagon like peptide (GLP) acting as dual agonist of GLP-1 receptor and glucagon receptor. It is based on lapscovery technology. The drug candidate is a new molecular entity (NME).
Merck is a biopharmaceutical company focused on the discovery, development, manufacturing and marketing of prescription medicines, biologic therapies, vaccines and animal health products. It offers prescription products for therapy areas related to cardiovascular, cancer, immune disorders, infectious, respiratory and women’s diseases, and diabetes. The company provides animal health products such as vaccines, poultry products, livestock products and aquaculture products. Merck sells medicines to drug wholesalers, retailers, hospitals, government agencies and managed health care providers; and animal health products to veterinarians, distributors and animal producers. The company and its subsidiaries operate in the Americas, Europe, the Middle East, Africa, Asia Pacific, and Latin America. Merck is known as MSD outside the US and Canada and is headquartered in Kenilworth, New Jersey, the US.
The company reported revenues of (US Dollars) US$59,283 million for the fiscal year ended December 2022 (FY2022), an increase of 21.7% over FY2021. The operating profit of the company was US$18,152 million in FY2022, compared to an operating profit of US$12,538 million in FY2021. The net profit of the company was US$14,519 million in FY2022, compared to a net profit of US$13,049 million in FY2021.
For a complete picture of Efinopegdutide’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.