Eurofins Scientific has patented a method to detect certain cancers in individuals by analyzing cell-free DNA for specific methylated CpGs. The method can determine the presence of cancer, particularly ovarian cancer in women, and guide treatment with specific chemotherapeutic agents or surgery. GlobalData’s report on Eurofins Scientific gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Eurofins Scientific, Telomerase reverse transcriptase screening was a key innovation area identified from patents. Eurofins Scientific's grant share as of February 2024 was 49%. Grant share is based on the ratio of number of grants to total number of patents.

Method to detect cancer in human individual using cell-free dna

Source: United States Patent and Trademark Office (USPTO). Credit: Eurofins Scientific SE

A recently granted patent (Publication Number: US11920200B2) outlines a method for detecting the presence of cancer in human individuals by analyzing cell-free DNA samples for methylation status at specific CpG sites. The patent describes a process where the presence of cancer is determined when at least one molecule of cell-free DNA is methylated at 16 CpGs. The method further includes treating the identified cancer by administering chemotherapeutic agents or performing tumor de-bulking surgery. The type of cancer and treatment options vary based on the gender of the individual, with specific cancers like breast, lung, colon, pancreatic, uterine, ovarian, and prostate cancers being targeted.

Additionally, the patent details the use of bisulfite as an agent to modify cell-free DNA based on CpG methylation status, amplification of specific nucleic acid sequences, and estimation of the fraction or ratio of methylated CpGs in the sample. The method also extends to individuals previously treated with carboplatin, where a reduced response to carboplatin therapy is determined based on methylation status at the 16 CpGs. In such cases, alternative chemotherapeutic agents are recommended for treatment. The patent emphasizes the importance of gender-specific cancer types and treatment strategies, highlighting the significance of personalized medicine in cancer care.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies