FS-120 is under clinical development by F-star Therapeutics and currently in Phase I for Solid Tumor. According to GlobalData, Phase I drugs for Solid Tumor have a 70% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how FS-120’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
FS-120 overview
FS-120 is under development for the treatment of solid tumors. The drug candidate is mAb-square immuno-regulatory bi-specific monoclonal antibody in which Fc region is replaced with Fcab region resulting in bi-specificity for two antigens. It is administered through intravenous route. The drug candidate is developed based on modular antibody technology.
F-star Therapeutics overview
F-star Therapeutics, a subsidiary of invoX Pharma Ltd, is a clinical-stage biopharmaceutical company that develops novel, innovative tetravalent bispecific antibodies for cancer and serious illnesses. The company’s pipeline products include FS118, FS120, FS222 and SB 11285. Its pipeline candidates treat rescuing clinical practice improvement (CPI) treatment failures and improving outcomes in the clinical practice improvement (CPI) naive, improving outcomes in programmed cell death ligand 1 (PD-L1) low tumors, improving CPI and chemotherapy outcomes. F-star Therapeutics partners programs include multiple blood-brain barriers, multiple immuno-oncology, STING inhibitors and multiple next-generation bispecific antibodies. The company works in partnership with Denali Therapeutics Inc, Merck KGaA and Takeda Pharmaceutical Company Limited. It operates in the UK and the US. F-star Therapeutics is headquartered in Cambridge, England, the UK.
For a complete picture of FS-120’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
