Gilead Sciences has been granted a patent for compounds and methods for treating viral infections. The patent includes the use of compounds in combination with other agents, salts, crystalline forms, and pharmaceutical compositions. GlobalData’s report on Gilead Sciences gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Gilead Sciences, Peptide pharmacophores was a key innovation area identified from patents. Gilead Sciences's grant share as of February 2024 was 46%. Grant share is based on the ratio of number of grants to total number of patents.

Treatment of viral infections with compounds and salts

Source: United States Patent and Trademark Office (USPTO). Credit: Gilead Sciences Inc

A recently granted patent (Publication Number: US11926645B2) discloses various crystalline forms of compounds, including those characterized by specific XRPD patterns and endothermic transitions. These crystalline forms are unsolvated and exhibit distinct XRPD patterns with specific degree 2?-reflections at various angles, indicating their unique crystalline structures. For example, some forms display endothermic events at specific temperatures, such as around 169°C, 154°C, or 186°C, showcasing their thermal properties.

Moreover, the patent also covers pharmaceutical compositions containing these crystalline forms along with pharmaceutically acceptable excipients. These compositions are intended for oral administration and can be used in methods of treating viral infections in humans, including coronavirus infections like SARS-CoV-2 (COVID-19). The patent claims encompass methods of administering specific crystalline forms to treat various viral infections caused by different virus families, highlighting the potential broad-spectrum antiviral applications of the disclosed compounds. Overall, the patent provides a detailed insight into the unique crystalline forms of the compounds, their pharmaceutical compositions, and their therapeutic uses in combating viral infections in humans.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies