Hisamitsu Pharmaceutical has patented a gel patch with ketoprofen for pain relief. The patch includes propylene glycol, 1-menthol, water, and a fatty acid alkyl ester like hexyl laurate or isopropyl palmitate. The propylene glycol mass is 3-fold the ketoprofen mass, with 1-menthol content at 0.1-0.5%. GlobalData’s report on Hisamitsu Pharmaceutical gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Hisamitsu Pharmaceutical, Microneedles for transdermal drug delivery was a key innovation area identified from patents. Hisamitsu Pharmaceutical's grant share as of February 2024 was 56%. Grant share is based on the ratio of number of grants to total number of patents.
A recently granted patent (Publication Number: US11903915B2) discloses a gel patch designed for transdermal drug delivery. The patch features a paste layer containing ketoprofen or its salt, propylene glycol, 1-menthol, water, and a fatty acid alkyl ester such as hexyl laurate or isopropyl palmitate. Notably, the mass of propylene glycol in the paste layer is limited to 3 times the mass of ketoprofen or less, ensuring optimal drug stability. Additionally, the content of 1-menthol in the paste layer falls within the range of 0.1 to 0.5 mass %, contributing to the overall efficacy of the patch.
Furthermore, the patent also outlines a method for stabilizing ketoprofen within the gel patch. By incorporating propylene glycol in a mass not exceeding 3 times that of ketoprofen, the method ensures the drug's stability over time. The paste layer, in addition to ketoprofen, propylene glycol, 1-menthol, and water, includes a fatty acid alkyl ester like hexyl laurate or isopropyl palmitate. This innovative approach to drug delivery through a gel patch offers a promising solution for efficient and controlled administration of ketoprofen, addressing the need for stable and effective transdermal drug delivery systems.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
