The pharmaceutical industry continues to be a hotbed of patent innovation. Activity is driven by by the evolution of treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 787,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Immuno-oncology in pharma: immunotherapy radiotherapy combination. Buy the report here.

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According to GlobalData’s Technology Foresights, which uses over 668,000 patents to analyze innovation intensity for the pharmaceutical industry, there are 80+ innovation areas that will shape the future of the industry.

Immunotherapy radiotherapy combination is a key innovation area in immuno-oncology

Combining immunotherapy with radiotherapy is a strategy that has shown promising results in cancer treatment. Immunotherapy activates the immune system to recognize and attack cancer cells, while radiotherapy is used to damage cancer cells. When used together, they enhance each other’s effects and lead to better treatment outcomes.

GlobalData’s analysis also uncovers the companies at the forefront of each innovation area and assesses the potential reach and impact of their patenting activity across different applications and geographies. According to GlobalData, there are 110+ companies, spanning technology vendors, established pharmaceutical companies, and up-and-coming start-ups engaged in the development and application of immunotherapy radiotherapy combination.

Key players in immunotherapy radiotherapy combination – a disruptive innovation in the pharmaceutical industry

‘Application diversity’ measures the number of applications identified for each patent. It broadly splits companies into either ‘niche’ or ‘diversified’ innovators.   

‘Geographic reach’ refers to the number of countries each patent is registered in. It reflects the breadth of geographic application intended, ranging from ‘global’ to ‘local’.  

Patent volumes related to immunotherapy radiotherapy combination

Company Total patents (2010 - 2022) Premium intelligence on the world's largest companies
Immunolight 160 Unlock Company Profile
Nanobiotix 128 Unlock Company Profile
Vertex Pharmaceuticals 117 Unlock Company Profile
Regeneron Pharmaceuticals 92 Unlock Company Profile
Les Laboratoires Servier 72 Unlock Company Profile
HitGen 61 Unlock Company Profile
Verneuil Participations 60 Unlock Company Profile
Pfizer 54 Unlock Company Profile
Omniox 48 Unlock Company Profile
Bayer 48 Unlock Company Profile
NH TherAguix 37 Unlock Company Profile
BioMarin Pharmaceutical 35 Unlock Company Profile
Cancer Research UK 35 Unlock Company Profile
Siemens 32 Unlock Company Profile
MetiMedi Pharmaceuticals 32 Unlock Company Profile
Tyme 28 Unlock Company Profile
Centre National de la Recherche Scientifique 24 Unlock Company Profile
Gilead Sciences 23 Unlock Company Profile
Diffusion Pharmaceuticals 20 Unlock Company Profile
Aprogen Biologics 20 Unlock Company Profile
Memorial Sloan Kettering Cancer Center 19 Unlock Company Profile
Calidi Biotherapeutics 18 Unlock Company Profile
AbbVie 17 Unlock Company Profile
Adastra Pharmaceuticals 16 Unlock Company Profile
MorEx Development Partners 16 Unlock Company Profile
Fumedica 16 Unlock Company Profile
Providence St. Joseph Health 15 Unlock Company Profile
Karyopharm Therapeutics 14 Unlock Company Profile
Aceragen 13 Unlock Company Profile
Daiichi Sankyo 12 Unlock Company Profile
E. Merck 12 Unlock Company Profile
Alpha Tau Medical 12 Unlock Company Profile
Shuttle Pharmaceuticals 12 Unlock Company Profile
F. Hoffmann-La Roche 12 Unlock Company Profile
Inovio Pharmaceuticals 11 Unlock Company Profile
Spectrum Pharmaceuticals 11 Unlock Company Profile
Regulon 11 Unlock Company Profile
Afimmune Biopharma 10 Unlock Company Profile
MEI Pharma 10 Unlock Company Profile
Neonc Technologies 10 Unlock Company Profile
PI Therapeutics 10 Unlock Company Profile
Firsthand Technology Value Fund 10 Unlock Company Profile
Help/Systems 10 Unlock Company Profile
Del Mar Pharmaceuticals (BC) 10 Unlock Company Profile
Merck 10 Unlock Company Profile
MiraDx 9 Unlock Company Profile
Vascular Biogenics 9 Unlock Company Profile
Centre Georges Francois Leclerc 9 Unlock Company Profile
GlycoMira Therapeutics 8 Unlock Company Profile
PT Soho Global Health 8 Unlock Company Profile

Source: GlobalData Patent Analytics

Immunolight is a biopharmaceutical company focused on advancing technologies to transform cancer treatment. The company developed a breakthrough technology that leverages the latest advances in energy transfer to establish high value innovations. The technology converts penetrating forms of energy, such as low dose X-Ray, into the ultraviolet part of the electromagnetic spectrum energies that can activate drugs inside the body, thereby triggering an immune response and creating a promising new approach to cancer treatment. Nanobiotix and Vertex Pharmaceuticals are some of the other key patent filers in immunotherapy radiotherapy combination.

In terms of application diversity, Aprogen Biologics leads the pack, while Merck and MetiMedi Pharmaceuticals stood in the second and third positions, respectively. By means of geographic reach, Les Laboratoires Servier held the top position, followed by HitGen and HitGen.

To further understand the key themes and technologies disrupting the pharmaceutical industry, access GlobalData’s latest thematic research report on Immuno-oncology (IO).

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Patent Analytics tracks patent filings and grants from official offices around the world. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.