IPH-6501 is under clinical development by Innate Pharma and currently in Phase II for Primary Mediastinal B-Cell Lymphoma. According to GlobalData, Phase II drugs for Primary Mediastinal B-Cell Lymphoma have an 82% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how IPH-6501’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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IPH-6501 overview
IPH-65 is under development for the treatment of solid tumors and relapsed or refractory B-cell non-Hodgkin's lymphoma, diffuse large b-cell lymphoma (DLBCL), thymic carcinoma, follicular lymphoma, mantle cell lymphoma, primary mediastinal (thymic) large B-cell lymphoma, marginal zone lymphoma (MZL) (nodal, extranodal or splenic) and marginal zone b-cell lymphoma. The drug candidate is a tetra-specific NK cell engager to engage activating receptors (NKp46 and CD16), a tumor antigen (CD20) and an interleukin-2 receptor and bind to tumor antigen on the cancer cells. It is developed based on NKCE technology.
Innate Pharma overview
Innate Pharma develops antibodies to treat cancer by harnessing the immune system. It offers Lumoxiti, a CD22-directed immunotoxin for the treatment of relapsed or refractory (r/r) hairy cell leukemia. The company is investigating Lacutamab, an anti-KIR3DL2 humanized cytotoxicity-inducing antibody for cutaneous T-cell lymphoma (CTCL), Monalizumab, an immune checkpoint inhibitor targeting solid tumors. Innate Pharma is also evaluating IPH5201, IPH5301, IPH6101, IPH6401, IPH6501 and IPH62 antibodies for the treatment of various tumors. It works in partnership with Sanofi SA, AstraZeneca Plc and other biopharmaceutical companies to develop its products. Innate Pharma is headquartered in Marseille, Provence Alpes Cote d’Azur, France.
For a complete picture of IPH-6501’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
