ITM-52 is under clinical development by ITM Isotope Technologies Munich and currently in Phase I for Non-Small Cell Lung Cancer. According to GlobalData, Phase I drugs for Non-Small Cell Lung Cancer have an 82% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how ITM-52’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

ITM-52 overview

ITM-52 is under development for the treatment of solid tumors (folate receptor alpha + tumors) including adenocarcinoma, non-small cell lung cancer (NSCLC) and ovarian cancer. The drug candidate comprises of folate receptor alpha (FR alpha) targeting molecule conjugated to the radioisotope 177 lutetium chloride (EndolucinBeta).

ITM Isotope Technologies Munich overview

ITM Isotope Technologies Munich (ITM) is a biotechnology company that develops and produces therapeutic and diagnostic radiopharmaceuticals and radioisotopes to treat cancer. Its product portfolio includes radiolabeling and quality control equipment includes iQS theranostics synthesizer, iQS Ga-68 fluidic labeling module and reagent set for manual labeling of NCA 177Lu and biomolecules. It also provides radiopharmaceuticals and medical radioisotopes includes endolucinbeta and TOCscan. ITM’s pipeline products include ITM-11 for neuroendocrine tumors (GEP-NETs); ITM-31 for glioblastoma; ITM-24D / ITM-22 for prostate cancer; ITM-55D and ITM-52 for ovarian cancer and NSCL adenocarcinoma; ITM-41 for osteosarcoma and bone metastases. It has laboratories manufacturing radiopharmaceuticals. ITM is headquartered in Munich, Bavaria, Germany.

For a complete picture of ITM-52’s drug-specific PTSR and LoA scores, buy the report here.


GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.