Radspherin is under clinical development by Oncoinvent and currently in Phase II for Colorectal Cancer. According to GlobalData, Phase II drugs for Colorectal Cancer have a 25% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Radspherin’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Radspherin overview

Radspherin, is under development for the treatment of metastatic cancers including peritoneal carcinomatosis originating from ovarian cancer, fallopian cancer, peritoneal cancer and colorectal cancer. It constitutes a monoclonal antibody OI-3 conjugated to a radioisotope or toxin. The drug candidate is a suspension of inorganic alpha-emitting radioactive microspheres and administered as intraperitoneal injection. It acts by targeting CD146 antigen.

Oncoinvent overview

Oncoinvent is a monoclonal antibodies product manufacturer. The company develops and manufactures therapeutic product for the treatment of various cancer. It develops Radspherin technology, an alpha-emitting radioactive microsphere, which is designed for treatment of metastatic cancers in body cavities. Oncoinvent’s Radspherin technology is an anticipated that the product can potentially treat several forms of metastatic cancer, ovarian cancer and colorectal cancer. It platforms through injections, medicines and liquids. The company carters its products under the brand Radspherin. Oncoinvent is headquartered in Oslo city, Oslo, Norway.

For a complete picture of Radspherin’s drug-specific PTSR and LoA scores, buy the report here.


GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.