Rocatinlimab is a monoclonal antibody commercialized by Amgen, with a leading Phase III program in Atopic Dermatitis (Atopic Eczema). According to Globaldata, it is involved in 14 clinical trials, of which 5 were completed, 8 are ongoing, and 1 is planned. GlobalData uses proprietary data and analytics to provide a complete picture of Rocatinlimab’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.

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The revenue for Rocatinlimab is expected to reach an annual total of $388 mn by 2037 in the US based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.

Rocatinlimab Overview

Rocatinlimab is under development for the treatment of atopic dermatitis. The drug candidate is a new molecular entity (NME). It is administered through intravenous and subcutaneous infusion. It is a monoclonal antibody and acts by targeting OX40. The drug candidate is based on POTELLIGENT antibody engineering technology. It was also under development for the treatment of moderate plaque psoriasis and ulcerative colitis .

Amgen Overview

Amgen is a biotechnology company, which discovers, develops, manufactures, and markets innovative human medicines to treat patients suffering from serious diseases. It develops novel medicines in therapeutic areas of cardiovascular, oncology/hematology, inflammation, bone health, neurological disorders and nephrology. The company develops products using advanced human genetics to analyze the difficulties of disease and understand the fundamentals of human biology. Amgen sells products primarily to pharmaceutical wholesale distributors in the US. It also markets certain products directly to consumers through direct-to-consumer channels and through partnerships with other companies. The company has presence in Asia Pacific, Europe, Middle East, North America and Australia. Amgen is headquartered in Thousand Oaks, California, the US.
The company reported revenues of (US Dollars) US$26,323 million for the fiscal year ended December 2022 (FY2022), an increase of 1.3% over FY2021. In FY2022, the company’s operating margin was 36.6%, compared to an operating margin of 29.4% in FY2021. In FY2022, the company recorded a net margin of 24.9%, compared to a net margin of 22.7% in FY2021. The company reported revenues of US$6,903 million for the third quarter ended September 2023, a decrease of 1.2% over the previous quarter.

For a complete picture of Rocatinlimab’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.

This content was updated on 20 February 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company.

The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s Pharmaceutical Intelligence Center.