SNG-1153 is under clinical development by Shenogen Pharma Group and currently in Phase I for Hepatocellular Carcinoma. According to GlobalData, Phase I drugs for Hepatocellular Carcinoma have an 81% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how SNG-1153’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
SNG-1153 overview
SNG-1153 is under development for the treatment of breast cancer, hepatocellular carcinoma, non-small cell lung cancer, chronic myeloid leukaemia (CML), melanoma and multiple myeloma(MM). It is the second generation small molecule which is developed based on the structure of icaritin. It acts by targeting estrogen receptor (ER)-alpha 36. It is developed based on selective estrogen receptor modulator (SERM) development platform.
It was also under development for endometrial cancer.
Shenogen Pharma Group overview
Shenogen Pharma Group Ltd (Shenogen) is a drug discovery and development company that develops therapeutics for cancer treatment. It develops biologic drugs and small molecule targeted at the new estrogen receptor variant. It provides SNG-162 that is a small molecule naturally derived a TCM. Shenogen is also developing second generation small molecule SNG-1153, which is ready for investigational new drug application. Shenogen offers other pipeline products such as SNG-8023 and companion diagnostic kit. The company provides solutions used in treatment of breast cancer, leukemia, prostate cancer and osteoporosis. Shenogen is headquartered in Beijing, China.
For a complete picture of SNG-1153’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
