Tildrakizumab is a Monoclonal Antibody owned by Sun Pharma Advanced Research Company, and is involved in 17 clinical trials, of which 11 were completed, and 6 are ongoing.
Tildrakizumab is an anti-interleukin (IL)-23A antibody. It works by selectively targeting IL-23, specifically the p19 component of the cytokine. IL-23 is a naturally occurring cytokine that are involved in inflammatory and immune responses, such as natural killer cell activation and CD4+ T-cell differentiation and activation. IL-23 has a role in chronic inflammation, which is a common characteristic of many autoimmune diseases. IL-23 promotes the Th17 pathway, which is active in the pathogenesis of inflammatory diseases, including psoriasis.
The revenue for Tildrakizumab is expected to reach a total of $9.2bn through 2038. This change impacts the valuation of this asset and is an important factor to understand the current value of the drug in a clinical process. View the complete picture with the Tildrakizumab NPV Report.
Tildrakizumab was originated by Schering-Plough and is currently owned by Sun Pharma Advanced Research Company. Sun Pharmaceutical Industries and Almirall are the other companies associated in development or marketing of Tildrakizumab.
Tildrakizumab (Ilumya, Ilumetri) is a monoclonal antibody, acts as an immunosuppressant agent. It is formulated as solution for subcutaneous route of administration. Tildrakizumab is indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.
Tildrakizumab is under development for the treatment of psoriatic arthritis and plaque psoriasis. It was also under development for ankylosing spondylitis and axial spondyloarthritis.
Sun Pharmaceutical Industries Overview
Sun Pharmaceutical Industries (Sun Pharma) is a specialty pharmaceutical company that offers a wide range of pharmaceutical formulations such as branded generics and generic pharmaceuticals. The company’s portfolio includes products for the treatment of psychiatric, neurological, nephrological, gastroenterological, orthopedic and ophthalmologic diseases and disorders, and heart diseases. The company carries out product development, process chemistry, and manufacture of complex formulations, active pharmaceutical ingredients (APIs) and over-the-counter products. It offers drugs in various dosage forms such as tablets, capsules, injectables, inhalers, ointments, creams, and liquids. The company has manufacturing facilities in North America, Latin America, EMEA and Asia Pacific. Sun Pharma is headquartered in Mumbai, Maharashtra, India.
The company reported revenues of (Rupee) INR386,544.9 million for the fiscal year ended March 2022 (FY2022), an increase of 15.4% over FY2021. In FY2022, the company’s operating margin was 9.1%, compared to an operating margin of 7% in FY2021. In FY2022, the company recorded a net margin of 8.5%, compared to a net margin of 8.7% in FY2021. The company reported revenues of INR109,522.8 million for the second quarter ended September 2022, an increase of 1.8% over the previous quarter.
Quick View – Tildrakizumab
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