Zatolmilast is under clinical development by Tetra Therapeutics and currently in Phase III for Fragile X Syndrome. According to GlobalData, Phase III drugs for Fragile X Syndrome does not have sufficient historical data to build an indication benchmark PTSR for Phase III. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the Zatolmilast LoA Report. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Zatolmilast overview
BPN-14770 is under development for the treatment of fragile X syndrome, traumatic brain injury and Alzheimer's disease. The drug candidate is administered through oral route. It acts by targeting enzyme phosphodiesterase 4 (PDE 4D) enzyme.
Tetra Therapeutics overview
Tetra Therapeutics, a subsidiary of Shionogi & Co Ltd, is a biotechnology company that researches and develops pharmaceutical drugs based on phosphodiesterase (PDE) sub-type inhibitors for neuroscience and non-neuroscience disorders. The company’s product pipeline includes BPN14770 PDE4D and pde4b inhibitors for the treatment of fragile x syndrome, Alzheimer’s disease (cognition), Alzheimer’s disease (inflammation), traumatic brain injury, progressive multiple sclerosis (MS) and chronic traumatic encephalopathy (CTE). It uses a structure-guided drug design chemistry approach to discover allosteric inhibitors of phosphodiesterase subtypes such as PDE4B and PDE4D. The company partners with various universities to commercialize intellectual property and conduct proprietary research on diseases affecting the central nervous system. Tetra Therapeutics is headquartered in Kalamazoo, Michigan, the US.
For a complete picture of Zatolmilast’s drug-specific PTSR and LoA scores, buy the report here.
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