Zealand Pharma has patented a method for producing acylated glucagon analogue peptides for treating obesity, diabetes, and metabolic disorders. The compound formula includes specific peptide sequences and fatty chain conjugates with polar groups. This innovation aims to target GLP-1 receptors effectively. GlobalData’s report on Zealand Pharma gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Zealand Pharma, Hormone-based therapies for metabolic disorders was a key innovation area identified from patents. Zealand Pharma's grant share as of January 2024 was 38%. Grant share is based on the ratio of number of grants to total number of patents.
The granted patent (Publication Number: US11884713B2) discloses a method for producing a compound with a specific chemical formula. The compound consists of a peptide sequence with defined amino acid residues and a unique residue denoted as ?. This ? residue is conjugated to a substituent with a specific structure, including a fatty chain with a polar group and a connection to another group at the end of the chain. The polar group can be a carboxylic acid or its bioisostere, a phosphonic acid, or a sulfonic acid group. The method involves modifying a precursor peptide to introduce this substituent at the designated residue ?, ensuring the compound's structural integrity and functionality.
Furthermore, the patent claims detail variations in the compound's structure based on the specific amino acid residues present in the peptide sequence and the nature of the substituent attached to the ? residue. The method outlined in the patent allows for the production of compounds with diverse properties and applications, depending on the precise combination of components. By following the steps described in the patent, researchers and manufacturers can create novel compounds with potential uses in various fields, including pharmaceuticals, biotechnology, and materials science. The patent's claims provide a framework for producing these compounds efficiently and reliably, paving the way for further innovation and development in the chemical and biological sciences.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
