ZL-1310 is under clinical development by Zai Lab and currently in Phase I for Small-Cell Lung Cancer. According to GlobalData, Phase I drugs for Small-Cell Lung Cancer have an 81% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how ZL-1310’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

ZL-1310 overview

ZL-1310 is under development for the treatment of small cell lung cancer. The therapeutic candidate is an antibody-drug conjugate (ADC) which acts by targeting cells expressing delta-like protein 3 (DLL3). It is being developed based on Tumor Microenvironment Activable LINker (TAMLIN) technology platform. It is administered through intravenous route.

Zai Lab overview

Zai Lab is a commercial-stage biopharmaceutical company. It discovers, develops and commercializes innovative products in the areas of oncology, autoimmune disorders, infectious disease and neuroscience. The company offers products such as niraparib, tumor-treating fields, efgartigimod, ripretinib and omadacycline. It’s pipeline products include tisotumab vedotin, adagrasib, repotrectinib, bemarituzumab, zipalertinib, ZL-1218, ZL-1310, sulbactam-durlobactam, KarXT, ZL-1102, ZL-8301, Efgartigimod PH20 SC, ZL-2308 (repotrectinib), ZL-1307 (REGN1979/odronextamab) and ZL-1218. Zai Lab commercializes its products under the brand names Optune, Qinlock, Zejula, NUZYRA and VYVGART. The company operates through its subsidiaries in Hong Kong, Taiwan, China, Australia and the US, among others. Zai Lab is headquartered in Shanghai, China.

For a complete picture of ZL-1310’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 20 May 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.