This document compares the performance of numerous single-use flexible transfer systems for use in OEB Level 5 containment, or where personal safety and cross-contamination are concerns. The DoverPac® system from ILC Dover was developed in collaboration with Eli Lilly and is designed solely for use with powders. The systems from other suppliers were not, and do not offer third-party SMEPA-tested performance test data. Their films also lack static dissipative properties, which could cause contamination, product discoloration and product to cling. Every DoverPac single-use container is also dwell-tested to ensure it operates as expected.