Johnson and Johnson HQ

Johnson & Johnson (JNJ) has completed the acquisition of Novira Therapeutics, a biopharmaceutical firm focused on developing new therapies for curative treatment of chronic hepatitis B virus (HBV) infection.

The companies have not disclosed the financial terms of the transaction, which was originally announced in November.

Discover B2B Marketing That Performs

Combine business intelligence and editorial excellence to reach engaged professionals across 36 leading media platforms.

Find out more

Novira is now part of the Infectious Diseases & Vaccines Therapeutic Area of the Janssen Pharmaceutical Companies of JNJ.

The acquisition includes Novira’s portfolio of new antivirals, including its lead candidate, NVR 3-778, an investigational small molecule, direct-acting antiviral.

NVR 3-778 is currently in Phase Ib clinical trials and is indicated for oral administration in patients with HBV that inhibits the HBV core or capsid protein involved in multiple activities required for the virus to replicate and persist.

"We will leverage our vast experience in viral diseases to develop potentially transformational medicines for HBV patients."

Janssen Research & Development global head William Hait said: "We are exploring several approaches in pursuit of a functional cure for this insidious disease.

GlobalData Strategic Intelligence

US Tariffs are shifting - will you react or anticipate?

Don’t let policy changes catch you off guard. Stay proactive with real-time data and expert analysis.

By GlobalData

"Bringing together NVR 3-778 with our own internal discoveries we will leverage our vast experience in viral diseases to develop potentially transformational medicines for HBV patients."

Across the world, HBV affects more than 350 million people and is a potentially fatal liver disease with around 60% of hepatocellular carcinoma cases being attributed to infection with the hepatitis B virus.

Janssen Pharmaceutical Companies is focused on addressing some of the most important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases.


Image: Johnson & Johnson Headquarters in New Brunswick, New Jersey. Photo: courtesy of Nikopoley.

Pharmaceutical Technology Excellence Awards - Nominations Closed

Nominations are now closed for the Pharmaceutical Technology Excellence Awards. A big thanks to all the organisations that entered – your response has been outstanding, showcasing exceptional innovation, leadership, and impact.

Excellence in Action
Awarded the 2025 Pharmaceutical Technology Excellence Award for Business Expansion in Integrated Manufacturing, Upperton Pharma Solutions is rapidly expanding its UK GMP and sterile manufacturing footprint. Find out how Upperton’s integrated CDMO model helps pharma companies move from early development to clinical and niche commercial supply with fewer handovers and faster timelines.

Discover the Impact