Vir Biotechnology and Alnylam Pharmaceuticals are going to collaborate on a RNAi therapeutics targeting to SARS-CoV-2 genome. Alnylam screened over 350 small interfering RNAs (siRNAs) to decide on one candidate – VIR-2703 – to progress into pre-clinical development.
The partners are hoping to meet with the FDA to discuss an accelerated path for filing an investigational new drug application at around the end of 2020.
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Vir CEO George Scangos said: “Vir is committed to applying industry-leading technologies in our fight against Covid-19.
“Our fruitful and expansive collaboration with Alnylam has rapidly led to identification of a development candidate targeting SARS-CoV-2.
“With this candidate now in hand, we will further accelerate our efforts and plan to begin studies in humans at or around year-end.
“Our ultimate goal would be to provide rapid worldwide access, if approved, to an effective therapeutic to combat Covid-19.”
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