Ypsomed - Pens, Pen Needles and Auto-Injectors for Self-Injection

Ypsomed is the largest independent developer and manufacturer of custom-made self-injection systems. Our injection pens, the core of our portfolio, range from simple disposable pens to reusable pens with variable dosing and electronic displays. Ypsomed also manufactures compatible pen needles with a unique click-on function for both our own and all other widely available pens.

Ypsomed is constantly expanding its core technology to cover new therapy and patient needs, including disposable and reusable auto-injector platforms for the treatment of autoimmune diseases and for new cancer therapies.

PEN INJECTORS - TYPICAL DOSING RANGE 0.01ML-0.8ML

Pen injectors are typically multi-dose injectors used mainly for frequent injections. Dosing can be fixed or variable. Injection pens are used with dedicated drug cartridges and pen needles.

The injection process (needle insertion and injection) is usually performed manually; needle-covers and spring-aided needle insertion or injection are optional. Ypsomed's patent-protected product range includes injection pens for single and dual-chamber cartridges and compatible pen needles.

REUSABLE INJECTION PENS

Ypsomed reusable injection pens are available with easy to read electronic displays for multiple dosing with optimal accuracy. Pens feature a simple 'start - dial - inject' system and clear audible feedback when dialling and delivering the dose.

DISPOSABLE AND SEMI-DISPOSABLE INJECTION PENS

Ypsomed disposable pens feature pull-push dose memory and minimum handling steps to provide maximum patient convenience. Our semi-disposable pens combine the ease of use of disposable pens with high-tech dosing mechanisms and dose displays.

REUSABLE PENS FOR STANDARD 3ML INSULIN CARTRIDGES

Ypsomed off-the-shelf reusable pens are designed for standard 3ml insulin cartridges. Doses range from 10µl to 600µl; they are ideal for phase II and III clinical trials.

PENFINE 'CLICK ON' PEN NEEDLES

Penfine patented click-on pen needles are available in sizes 6mm and 8mm x 31G, and 10mm and 12mm x 29G.

AUTO-INJECTORS - TYPICAL DOSING RANGE 0.5ML - 1ML

Ypsomed's patent-protected auto-injector technology focuses on the key features of safe injection release mechanisms, injection feedback, and needle safety. Our disposable and reusable auto-injector platforms are compatible with standard 1ml-long pre-filled syringes.

DISPOSABLE AND REUSABLE AUTO-INJECTORS

Ypsomed's patented disposable auto-injector is the shortest device available for 1ml syringes, and features:

• Button 'interlock' activation
• Audible 'end-of-injection' feedback
• Passive needle safety

Ypsomed's reusable auto-injector is designed specifically for SSI's Ultra-Safe® passive safety syringe system. The patented two-stage injection device is the first reusable auto-injector to provide complete needle safety.

SELECTING THE BEST SELF-INJECTION DEVICE FOR YOUR DRUG THERAPY

Ypsomed works closely with its partners to select the most appropriate device technology based on key considerations, such as:

• Type of device - pen, auto-injector, reusable, disposable, or semi-disposable
• Frequency of injection, reimbursement considerations and risks related to needle-stick injuries
• Use of standard primary drug reservoir for different devices, each dedicated to particular patient groups
• Proportion of patients self-injecting compared with those receiving the injection from healthcare professionals

YPSOMED - INNOVATION AND RELIABILITY

A broad-based technology platform and over 150 patent families allow Ypsomed to meet virtually all partner needs. Internal capabilities include R&D, tool-making, injection moulding, clean room production and assembly facilities.

Ypsomed provides the production expertise according to the latest regulatory requirements for both low and high volume production. We manufacture in FDA-registered facilities, are inspected regularly by its customers and regulatory authorities, and supply devices approved for all leading markets.

Ypsomed has well-established partnerships of many years with numerous leading pharmaceutical and biotech manufacturers such as Sanofi-Aventis, Genentech, Lilly, Pfizer, Roche and Serono. We have a solid base and are a recognised pioneer in our industry, with over 19 years’ experience (formerly as Disetronic Injection Systems) and well-established links to cartridge and syringe manufacturers and fillers.