Huadong Medicine has been granted a patent for a multi-domain active protein designed to treat metabolic diseases. The protein has a long half-life, increased GLP-1R agonist activity, and low immunogenicity potential. Its simplified recombinant preparation process sets it apart from existing treatments. GlobalData’s report on Huadong Medicine gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Huadong Medicine, was a key innovation area identified from patents. Huadong Medicine's grant share as of February 2024 was 50%. Grant share is based on the ratio of number of grants to total number of patents.

Multi-domain active protein for treating metabolic diseases

Source: United States Patent and Trademark Office (USPTO). Credit: Huadong Medicine Co Ltd

A recently granted patent (Publication Number: US11858975B2) discloses a multi-domain active protein with a unique structure aimed at promoting weight loss and treating metabolic and related diseases. The protein comprises a specific arrangement of active peptides, long-acting protein units, and native or analogue proteins. The amino acid sequence of the active peptide is selected from specific sequences provided in the patent.

The patent also covers methods for preparing the multi-domain active protein, including culturing host cells under suitable conditions, isolating and purifying the protein. Additionally, it includes compositions containing the active protein and a pharmaceutically acceptable carrier for administration to subjects in need of weight loss or treatment for metabolic diseases. The patent further extends to methods for promoting weight loss by administering the disclosed compositions to subjects, emphasizing the potential therapeutic applications of the multi-domain active protein in addressing metabolic disorders.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies