ZB-004 is under clinical development by Zenas BioPharma (USA) and currently in Phase I for Autoimmune Disorders. According to GlobalData, Phase I drugs for Autoimmune Disorders have a 73% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how ZB-004’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
Discover B2B Marketing That Performs
Combine business intelligence and editorial excellence to reach engaged professionals across 36 leading media platforms.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
ZB-004 overview
ZB-004 (XmAb-10717) is under development for the treatment of autoimmune diseases. The therapeutic candidate is a extended Fc fusion protein being developed based on Xmab technology platform. It is administered through subcutaneous route and acts by targeting CTLA-4.
Zenas BioPharma (USA) overview
Zenas BioPharma (USA) (Zenas) is a biopharmaceutical company that provides the development and commercialization of immunology-based therapies. The company pipeline product includes Obexelimab (ZB012), ZB002, ZB004, ZB001/011 and ZB005. Its product pipeline indications include IgG4-related disease, warm autoimmune haemolytic anaemia (wAIHA), thyroid eye disease and autoimmune disorders. Zenas collaborates with business partners such as Xencor, Inc., Viridian Therapeutics, Inc., and Dianthus Therapeutics to drive operational excellence and deliver potentially transformative therapies. Zenas is headquartered in Waltham, Massachusetts, the US.
For a complete picture of ZB-004’s drug-specific PTSR and LoA scores, buy the report here.
Data Insights
From
The gold standard of business intelligence.
Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.
GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
