The rise of ADCs in oncology: how antibody drug conjugate therapies deliver precision
An antibody drug conjugate links a tumor-binding antibody to a potent small-molecule payload through a designed chemical linker. The aim…
All articles by Miranda Mclaren
Miranda Mclaren
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From compliance to culture: Lessons from a quality leader on pharma’s next imperative
We spoke with Grace Breen, Senior Vice President, Quality at Sharp about the role of quality in a CDMO environment,…
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Peptides in the pipeline: How companies are overcoming the early-stage challenges
Much larger than traditional small molecule drugs, peptides enable rapid tissue penetration while retaining the selectivity and potency of a…
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How biopharma is scaling sterile manufacturing in 2026
Aseptic manufacturing plays a crucial role in the pharmaceutical supply chain, ensuring sterility for complex injectable biologics. In recent years,…
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Extracellular vesicles: The next frontier in regenerative medicine and drug delivery?
Extracellular vesicles (EVs) are tiny, membrane-bound particles released by every cell type studied to date. Though small, they carry a…
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Navigating uncertainty and building resilient supply chains: The case for US-based CDMO partnerships
Choosing to onshore pharmaceutical manufacturing by partnering with a US-based contract development and manufacturing organization (CDMO) can offer advantages for…
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Dermatology Trials by the Numbers: Key Trends and Benchmarks for 2026
Dermatology - spanning chronic inflammatory disease, infection, wound healing, pigment disorders, hair loss and rare genetic conditions - is nothing…
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Doubling down on efficacy: Exploring the potential of dual-payload ADCs
Chemotherapy has been our main weapon against late-stage cancers for decades, bringing with it wide-ranging side effects caused by the…
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Potency assays in cell therapies: A look behind the challenges
Dr. Scott Jones has spent more than 35 years advancing assay development and currently leads BioBridge Global’s R&D department. His…
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Bile acid modulators in discovery: Identifying cholestasis candidates with the best chance of success
Disrupted bile flow, or cholestasis, is a key feature of various chronic liver diseases such as primary biliary cholangitis (PBC)…