Meeting in Nairobi in December 2017, the UN Environment Assembly committed to a new resolution, urging all countries to prevent and significantly reduce marine pollution of all kinds, in particular from land-based activities’ by 2025. It claims, unless action is taken, oceans will contain more plastic than fish by 2050.

This call to action is increasing and businesses across all sectors are preparing for the global fight against disposable plastic packaging.

Head of new product development and innovation at Origin Jon Lant discusses how businesses in the pharmaceutical industry can evaluate current processes to remain both cost-effective and reduce plastic waste.

Alternative materials and technologies

According to the UK Government, plastic waste in the oceans will treble in the next decade, as each piece takes hundreds of years to break down. Of course, it’s the responsibility of businesses to help take action against plastic waste, but this will inevitably cause challenges for the pharmaceutical market.

There is more research taking place around bio-based polyethene (PE) and bio-based polyethene terephthalate (PET), as these materials are easily recyclable alongside their conventional counterparts in existing recycling streams. Bio-based PET is made from ethylene derived from sugarcane. Cultivation of sugarcane utilises carbon dioxide and releases oxygen, which means it also has a negative carbon footprint.

Some of the latest applications for alternative forms of plastic include pioneering new technology converting PET waste back into virgin grade material for use. It works by taking non-recycled PET waste such as coloured bottles and breaking it down to base molecule level, while separating the colour and other contaminants.

The molecules are converted back into PET, which is equal to virgin-grade quality. The technology has successfully passed its pilot stage and is now moving towards testing at an industrial scale.

Eco-friendly production

The right design and manufacturing processes can significantly reduce waste and reliance on energy, creating a final product with a lower carbon footprint. As a heavily regulated industry, we are not always the best at collaboration, yet there is barely an industry not affected by the cry for alternative materials, so it’s important to focus on developing solutions.

3D printers are cutting back on waste during the research and development (R&D) stages of pack development, as it slowly adds material to an item until it is complete. Most other manufacturing methods are subtractive, but with additive manufacturing you are building objects from the bottom up and only using the material you need.


3D printing can also accelerate early-stage product development through rapid prototyping. It helps companies design several moulds so these can be manufactured quickly and economically. Thus, it can rapidly expedite the time and cost it takes to bring a product to market.

Minimising waste

Part of the solution for cutting plastic waste is to reduce the total amount of packaging produced overall. We should focus on optimising the materials we already use alongside technology, which is developing within production processes, to deliver material intelligently within the moulding process.

Rheological, thermal and mechanical mould design with the help of a wide variety of software solutions, and is part of the answer to reducing waste in the design and processing stages. Furthermore, computer-aided design (CAD) and computer-aided manufacturing (CAM) allows close tolerances during the mould-making stages, which further enhances accuracy.

We also need to look beyond packaging and consider how innovations in formulations and dispensing can reduce the quantity of packaging needed to deliver products.

A good example of this is the innovative tamper-evident design of two-in-one vials for pharmaceuticals. These enable consumers to easily determine the authenticity of a product and takes the guesswork out of mixing drugs, so there is less waste. There is less chance of contamination and it’s a cost-effective solution versus traditional glass vials.

Innovations are occurring across temperature-controlled packaging as well. A standard characteristic is many different dimensions are necessary to account for any change in mass or volume. However, pharma industries are working on solutions which do not require a comparable variety of components and therefore have smaller overall dimensions.

Reshape the materials’ economy one step at a time

A new report suggests applying circular-economy principles to global plastic-packaging flows could reshape the materials’ economy. It could drastically reduce negative externalities, such as leakage into oceans as plastics escape established waste-collection systems.

To create an effective after-use plastics economy, the pharma industry should start to establish a cross-value chain dialogue and industry-wide plastics protocol to substantially improve the collection, sorting and reprocessing yields and quality, while allowing for regional differences.

Focus on key innovation opportunities that have the potential to scale up should continue, such as investments in new or improved materials and reprocessing technologies. There needs to be a continued focus on adopting reusable and industrially compostable plastic packaging when possible too.

While there remains a degree of scepticism regarding the detail, nature and geographical source of global plastic waste, there is clearly no time to be lost in addressing the bigger issue.  There are aspects to the plastics crisis within our control and opportunities to demonstrate our commitment as an industry and as a nation to lead and pioneer in the realisation of a safer, sustainable environment.